TruthNexus
Clinical Decision Support · Medical

Validated CDS rules ready to deploy today

Health systems either build CDS rules internally — expensive and slow — or rely on uncalibrated alerts already in their EHR. Clinicians ignore more than 80% of those alerts. The CDSS Marketplace offers pre-validated, evidence-calibrated rules with EHR-native integration — browse, customize, and deploy in hours.

80%+
Of generic CDS alerts ignored by clinicians
ECE <0.10
Confidence calibration on every rule
Epic / Cerner
Native CDS Hooks integration
Level 1–2
Minimum evidence standard per rule
Capabilities

What the CDSS Marketplace does

Pre-built rules across specialties

Curated library covering cardiology, endocrinology, infectious disease, neurology, and general medicine — each ECE-calibrated with confidence scores below 0.10 and clinical evidence cited per recommendation.

Evidence chain transparency

Every rule shows the clinical guidelines, trials, and confidence basis behind each recommendation. Clinicians can click through to the evidence — not just accept an alert.

Direct EHR deployment

Epic CDS Hooks (order-select, patient-view), Cerner HealtheLife, and athenahealth integrations with SMART on FHIR support. Deploy a validated rule in hours, not months.

Performance testing before deployment

Sensitivity, specificity, PPV, NPV, and AUC reported on every rule before deployment — with ECE calibration date. Know exactly how a rule will perform in your patient population.

Who It's For

Hospital systems, EHR vendors, and specialty practices

Hospital Systems
Deploy CDS across multiple facilities with consistent evidence calibration — and customize thresholds per system protocol.
EHR Vendors
Build premium evidence-calibrated CDS content into your platform without building the evidence layer from scratch.
Specialty Practices
Cardiology, oncology, and infectious disease specialty packs with guideline-current recommendations.
Health Plans
Automate prior authorization decisions with evidence-grounded criteria validated against the same guidelines payers already use.
Regulatory

Medical device software standards met

Rules conform to IEC 62304 medical device software standards, FDA SaMD AI/ML guidance, ISO 14971 risk management, and IEC 82304-1 health software requirements. All rules require Level 1 or Level 2 evidence and guidelines published within the past 5 years.

HIPAA-compliant with SOC 2 Type II certification in progress (target Q4 2026). BAA available for health system deployments.

HIPAA ReadyIEC 62304FDA SaMDSOC 2 Type II · Q4 2026TEFCA QHIN
Pricing

Start with one rule. Scale to a system-wide library.

Every tier includes ECE calibration report, evidence chain documentation, and EHR integration package. Rules are updated when the underlying clinical evidence changes — not on a fixed annual cycle.

Per Rule
$500 – $5K
per rule

Single validated rule with evidence chain, ECE report, and EHR integration package. Suitable for targeted alert replacement.

Specialty Pack
$10K – $50K
per specialty

Full rule library for one specialty (cardiology, endocrinology, infectious disease, neurology, or general medicine) with deployment support.

Enterprise
$100K – $500K
per year

Full library access across all specialties, custom rule development, white-label option, dedicated integration support, and SLA-backed updates.

Custom Development
Quoted

Institution-specific rules built to your protocols, evidence-calibrated and integrated into your EHR workflow. Priced by scope.

All tiers include BAA for health system deployments. Custom development scoped on request.

CMS CMMI ACCESS Model · July 2026

CMS launched the CMMI ACCESS model to accelerate evidence-based clinical decision support across Medicare and Medicaid. Participating health systems and payers receive financial incentives for deploying validated, evidence-grounded CDS. Skippy CDSS Marketplace rules meet the evidence calibration and audit trail requirements for CMMI ACCESS participation.

See the CDSS Marketplace in your EHR

We work with hospital systems, EHR vendors, and specialty practices. Let's talk about your clinical decision support deployment.